Benadryl side effects long term - Oct 6, 2015 · Caution should be exercised for long-term use of Benadryl (diphenhydramine), an antihistamine and a non-benzodiazepine sedative-hypnotic, because of the association of increased risk for dementia.

 
What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc .... Sergeant

Common Benadryl (diphenhydramine) side effects include drowsiness, dizziness, and blurry vision. Dry mouth and constipation are common, as well. Serious Benadryl side effects include a greater risk of falls — especially if you are an older adult — and potential long-term memory problems.Nov 14, 2022 · A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ... There could be both short- and long-term consequences. Worried about the side effects of Ambien, Lunesta or other sleep aids? ... Diphenhydramine is an anticholinergic drug, which means it blocks ...May 8, 2019 · Answer. While Benadryl ( diphenhydramine) can safely be used once in a while as a sleep aid, long-term use is not recommended for multiple reasons. Even the intermittent use of Benadryl for sleep isn't generally recommended if you are elderly (over 65). Studies show that the elderly population doesn't metabolize Benadryl as quickly and are far ... skin rash. swollen joints. stomach discomfort, upset or pain. tender swollen glands in neck. tremor. unusual excitement, nervousness, restlessness, or irritability. vomiting. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.Benadryl may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of diphenhydramine. Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine.Oct 9, 2018 · Many older adults may take sleeping pills because pain, nerve problems or other health issues are keeping them up at night, she says. For these people, a sleeping pill is standing in the way of ... Answer (1 of 2): Here is one long term study: “These drugs are called anticholinergics, among them the first-generation antihistamines that are now marketed as sleep aids.Long-term side effects Over-the-counter Benadryl is approved for temporary or short-term use and is not intended for long-term use. There is very little scientific research about the long-term ...Diphenhydramine (Benadryl) is a common over-the-counter allergy medication. It’s part of a class of drugs called anticholinergics that research has linked to dementia in older people.Jan 10, 2023 · hoarseness. lack or loss of strength. pain in the lower back or side. swelling of the hands, feet, or lower legs. trembling or shaking. Common side effects that do require medical attention ... The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ...Sep 14, 2022 · Benadryl helps reduce the effects of natural chemicals in the body called histamines. It is used to treat the side effects of an allergic reaction, including: Benadryl can be taken to relieve the symptoms of hayfever (seasonal allergies) and motion sickness. It can also be taken to induce sleep and treat certain symptoms of Parkinson's disease. “Atarax (hydroxyzine) and Benadryl (diphenhydramine) were routinely administered in the chemotherapy I received for breast cancer. After 5 months of chemo, I attributed my loss of mental function to a condition I read about called “chemo brain” — and chalked it up as another price paid in side affects for the benefit of staying alive.May 17, 2018 · Answer From Eric J. Olson, M.D. It's unlikely you'll become dependent on zolpidem (Ambien). Ambien and similar sleep medications can be effective, and they're much less likely to be habit-forming than some other drugs sometimes prescribed for sleep problems — for example, benzodiazepines, such as alprazolam (Xanax), lorazepam (Ativan) or ... Aug 1, 2023 · skin rash. swollen joints. stomach discomfort, upset or pain. tender swollen glands in neck. tremor. unusual excitement, nervousness, restlessness, or irritability. vomiting. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Answer From Eric J. Olson, M.D. It's unlikely you'll become dependent on zolpidem (Ambien). Ambien and similar sleep medications can be effective, and they're much less likely to be habit-forming than some other drugs sometimes prescribed for sleep problems — for example, benzodiazepines, such as alprazolam (Xanax), lorazepam (Ativan) or ...Benadryl Addiction Side Effects. Despite having numerous benefits in the medical world, Benadryl has its share of negative side effects when abused. Some effects are short term whereas others can last a lifetime. A user can either encounter psychological effects, physical effects, or both. Some of the physical effects to watch out for include ...Long-Term Side Effects of Diphenhydramine Abuse. Continued diphenhydramine use can cause long-term adverse side effects that result in permanent damage. Not only will prolonged use cause harm, but it can lead to other aspects such as dependence on the medication. Common long-term side effects of prolonged diphenhydramine use include: Dependence. Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache.Some dosage forms listed on this page may not apply to the brand name Benadryl Allergy. Summary. More frequent side effects include: sedated state and thickening of bronchial secretions. Continue reading for a comprehensive list of adverse effects. Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include:Anxiety. Asthma. Car Sickness. Insomnia. Motion sickness. Reactions to Vaccines. Because one of the common side effect of Benadryl in dogs is drowsiness, your vet may use it to alleviate dog anxiety, particularly associated with traveling and motion sickness that may occur during plane rides or car trips.What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ...Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above.May 8, 2019 · Answer. While Benadryl ( diphenhydramine) can safely be used once in a while as a sleep aid, long-term use is not recommended for multiple reasons. Even the intermittent use of Benadryl for sleep isn't generally recommended if you are elderly (over 65). Studies show that the elderly population doesn't metabolize Benadryl as quickly and are far ... May 19, 2022 · Yes, certain side effects are possible after using Benadryl long term. For example, long-term use of Benadryl may cause: an increased risk of dementia; withdrawal symptoms after the drug is stopped* However, keep in mind that doctors typically don’t recommend taking Benadryl as a long-term treatment. There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria)Inhaled corticosteroids are often used daily as part of treatment for asthma caused or complicated by reactions to airborne allergy triggers (allergens). Side effects are generally minor and can include mouth and throat irritation and oral yeast infections. Some inhalers combine corticosteroids with long-acting bronchodilators.Jan 10, 2023 · hoarseness. lack or loss of strength. pain in the lower back or side. swelling of the hands, feet, or lower legs. trembling or shaking. Common side effects that do require medical attention ... Oct 3, 2022 · Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating. General The most commonly reported side effects included somnolence, dizziness, and incoordination. Oct 3, 2022 · Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include: Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions. Oct 3, 2022 · Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include: Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions. Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose.Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating. General The most commonly reported side effects included somnolence, dizziness, and incoordination.Hives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ...Jul 5, 2023 · Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect. 5. Tips. Benadryl may be taken with or without food. Take exactly as directed. Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose.Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom).May 17, 2019 · Diphenhydramine, which is the active ingredient in ZzzQuil, can cause side effects in some people. The most common side effects of diphenhydramine include: drowsiness. dizziness. loss of ... Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago.Jan 10, 2023 · hoarseness. lack or loss of strength. pain in the lower back or side. swelling of the hands, feet, or lower legs. trembling or shaking. Common side effects that do require medical attention ... The Major Antihistamine Effects of Diphenhydramine Prevents Histamine-Mediated: constriction of respiratory smooth muscle. rapid vasodilation in blood vessels. increased capillary permeability and subsequent edema. sensations of itching, pain, and “flare” formation. increase in heart rate and strength of contraction.IV administration of 50 mg of DPH resulted in immediate improvement of tremor, rigidity, tachycardia, and eye versions. The patient was started on oral DPH 50 mg 4 times a day and the dose was reduced by 25% every 3 days. Oral clonidine 0.1 mg 3 times a day and a weekly 0.1 mg transdermal patch was added to mitigate sympathetic side effects.Apr 6, 2023 · Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https ... Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, beExamples of Viagra’s more commonly reported side effects include: headache. flushing (temporary warmth, redness, or deepening of skin color) stuffy nose. indigestion (upset stomach) mild vision ...May 13, 2021 · The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ... “Atarax (hydroxyzine) and Benadryl (diphenhydramine) were routinely administered in the chemotherapy I received for breast cancer. After 5 months of chemo, I attributed my loss of mental function to a condition I read about called “chemo brain” — and chalked it up as another price paid in side affects for the benefit of staying alive.Benadryl may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of diphenhydramine. Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine.It can sometimes cause a decrease in memory, confusion, and thinking issues. These side effects are more common in elders. In addition, taking Benadryl long-term might increase the risk of dementia. People aged> 65 who took medications such as Benadryl daily for over three years had an increased risk of dementia.Jun 6, 2023 · Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above. Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https ...Jun 6, 2023 · Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above. A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ...Jun 5, 2019 · Moderate and Severe Benadryl Side Effects. If patients are using Benadryl for an allergic reaction, and experience any of the following moderate to severe Benadryl side effects they should consult their medical doctor or contact emergency medical services to minimize injury to their health: Contact and Atopic dermatitis ~1.0-10.0%; Confusion Common Side Effects of Diphenhydramine. Diphenhydramine is considered an H1 receptor antagonist, and it works by blocking the effect of histamine in the body. The chemical reactions that diphenhydramine trigger in the body can cause other potentially significant sedative side effects on the central nervous system (CNS).Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning. Diphenhydramine increased the risk of dementia by 54% in one 3,000 patient study followed for seven years. Apr 11, 2023 · In the drug realm, antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), cetirizine (Zyrtec), and loratadine (Claritin) can help with a stuffy nose are safe for the heart. Nasal sprays deliver a decongestant right where you need it. In theory, this should minimize cardiovascular effects. May 8, 2019 · Answer. While Benadryl ( diphenhydramine) can safely be used once in a while as a sleep aid, long-term use is not recommended for multiple reasons. Even the intermittent use of Benadryl for sleep isn't generally recommended if you are elderly (over 65). Studies show that the elderly population doesn't metabolize Benadryl as quickly and are far ... Jun 23, 2009 · The most common side effect is drowsiness, causing mild disorientation or dementia. An elderly person may fall asleep during normal activities. This sedating effect can cause unsteadiness. A person over 60 should get up slowly from a sitting or prone position to avoid fainting. If you take an anti-anxiety drug, it is not advisable to use ... General The most commonly reported side effects included somnolence, dizziness, and incoordination. [ Ref] Nervous system Common (1% to 10%): Sedation/somnolence/sleepiness, drowsiness, unsteadiness, dizziness, headache, attention disturbance Rare (0.01% to 0.1%): Extrapyramidal effects, tremor, convulsionsWhile there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:Official answer. Diphenhydramine can be used as a short-term sleep aid to help ease occasional sleep problems. Older adults, children under age 16 and pregnant women should avoid taking diphenhydramine, as the risks to these groups may outweigh the benefits. Diphenhydramine should not be taken as a treatment for chronic insomnia. Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating. General The most commonly reported side effects included somnolence, dizziness, and incoordination.Long-Term Side Effects of Diphenhydramine Abuse. Continued diphenhydramine use can cause long-term adverse side effects that result in permanent damage. Not only will prolonged use cause harm, but it can lead to other aspects such as dependence on the medication. Common long-term side effects of prolonged diphenhydramine use include: Dependence. Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago.Impaired concentration. Memory difficulties. Anxiety. Stomach disturbances. Nausea and vomiting. A dry mouth. Constipation. Liver problems, etc. In certain people, a paradoxical reaction to diphenhydramine is possible, meaning that the drug causes different symptoms than the intended ones.Aug 15, 2023 · It can sometimes cause a decrease in memory, confusion, and thinking issues. These side effects are more common in elders. In addition, taking Benadryl long-term might increase the risk of dementia. People aged> 65 who took medications such as Benadryl daily for over three years had an increased risk of dementia. There could be both short- and long-term consequences. Worried about the side effects of Ambien, Lunesta or other sleep aids? ... Diphenhydramine is an anticholinergic drug, which means it blocks ...Long-term use of Benadryl can also lead to constipation and confusion. Interactions. Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine. IV administration of 50 mg of DPH resulted in immediate improvement of tremor, rigidity, tachycardia, and eye versions. The patient was started on oral DPH 50 mg 4 times a day and the dose was reduced by 25% every 3 days. Oral clonidine 0.1 mg 3 times a day and a weekly 0.1 mg transdermal patch was added to mitigate sympathetic side effects.But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ...May 7, 2021 · There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria) Giving Benadryl to dogs long term in some cases can be helpful for the dog. However, one of the main side effects of Benadryl is drowsiness. Giving too much dog Benadryl can cause the dog to go into a deep sleep for some time. Additionally, in some cases Benadryl can cause upset stomach and even possibly loss of appetite.Jun 15, 2016 · IV administration of 50 mg of DPH resulted in immediate improvement of tremor, rigidity, tachycardia, and eye versions. The patient was started on oral DPH 50 mg 4 times a day and the dose was reduced by 25% every 3 days. Oral clonidine 0.1 mg 3 times a day and a weekly 0.1 mg transdermal patch was added to mitigate sympathetic side effects. Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. 1. McMillan JM, Aitken E, Holroyd-Leduc JM. Management of insomnia and long-term use of sedative- hypnotic drugs in older patients. CMAJ 2013;185:1499–505. [ PMC free article] [ PubMed] [ Google Scholar] 2. Gray SL, Anderson ML, Dublin S, et al. Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study.Dec 1, 2022 · Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ... Oct 3, 2022 · Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth. Fixed combination loratadine (the active ingredient contained in Claritin) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue. Common Side Effects of Diphenhydramine. Diphenhydramine is considered an H1 receptor antagonist, and it works by blocking the effect of histamine in the body. The chemical reactions that diphenhydramine trigger in the body can cause other potentially significant sedative side effects on the central nervous system (CNS).Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Not able to pass urine or change in how much urine is passed. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis) may happen.When corrected based on the number of drugs with anticholinergic effects an individual was taking, the odds ratio for cognitive impairment was 1.46 with a p value of .0181. However, overall the authors conclude that their data did not support the hypothesis that the use of anticholinergic medications increased the risk of alzheimer’s dementia ...Diphenhydramine, which is the active ingredient in ZzzQuil, can cause side effects in some people. The most common side effects of diphenhydramine include: drowsiness. dizziness. loss of ...Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This article is for information only. DO NOT use it to treat or manage an actual overdose.

May 17, 2018 · Answer From Eric J. Olson, M.D. It's unlikely you'll become dependent on zolpidem (Ambien). Ambien and similar sleep medications can be effective, and they're much less likely to be habit-forming than some other drugs sometimes prescribed for sleep problems — for example, benzodiazepines, such as alprazolam (Xanax), lorazepam (Ativan) or ... . Tmp2 il progetto

benadryl side effects long term

Nov 15, 2017 · Asthma. Car Sickness. Insomnia. Motion sickness. Reactions to Vaccines. Because one of the common side effect of Benadryl in dogs is drowsiness, your vet may use it to alleviate dog anxiety, particularly associated with traveling and motion sickness that may occur during plane rides or car trips. Diphenhydramine is contraindicated in premature infants and neonates, as well as people who are breastfeeding. It is a pregnancy Category B drug. Diphenhydramine has additive effects with alcohol and other CNS depressants. Monoamine oxidase inhibitors prolong and intensify the anticholinergic effect of antihistamines. OverdoseBenadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above.The most common side effect is drowsiness, causing mild disorientation or dementia. An elderly person may fall asleep during normal activities. This sedating effect can cause unsteadiness. A person over 60 should get up slowly from a sitting or prone position to avoid fainting. If you take an anti-anxiety drug, it is not advisable to use ...Uses Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough,... General The most commonly reported side effects included somnolence, dizziness, and incoordination. [ Ref] Nervous system Common (1% to 10%): Sedation/somnolence/sleepiness, drowsiness, unsteadiness, dizziness, headache, attention disturbance Rare (0.01% to 0.1%): Extrapyramidal effects, tremor, convulsionsApr 8, 2023 · The main long-term side effects of Plaquenil are eye-related. ... To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine ... • Common side effects of montelukast include upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection. Apr 11, 2018 · Benadryl is a first-generation antihistamine, meaning it is one of the earlier drugs developed in this category of medications. First-generation antihistamines, like Benadryl, are often noted for their sedative side effects as they have the ability to travel to your brain (i.e. crosses the blood-brain barrier), which is why they can make you ... Benadryl dosage for dogs. The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to ...Dec 1, 2022 · Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ... May 13, 2021 · The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ... Long-Term Side Effects of Diphenhydramine Abuse. Continued diphenhydramine use can cause long-term adverse side effects that result in permanent damage. Not only will prolonged use cause harm, but it can lead to other aspects such as dependence on the medication. Common long-term side effects of prolonged diphenhydramine use include: Dependence. .

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